- PHARMA ALLIANCE GRUP has added EMD-21 PDO to its range of dissolution media preparators. This product offers a combination of proven, high-quality deaeration of dissolution media that can be used under a stringent quality management system in a GMP environment with reliable measurement of the effectiveness of deaeration (dissolved oxygen). The media preparatory is primarily designed for high-throughput laboratories where speed, convenience, reliability and cost-effectiveness are high priorities and where bench space is scarce. This rugged product ensures speedy deaeration of 21 L of media in just 25 min, attaining a post-deaeration dissolved oxygen level of <4 ppm. Single batch dearation minimizes inter-vessel variation and allows filling of dissolution vessels for up to three dissolution tests (n=6). The specially designed nozzle allows deaeration of surfactants like sodium lauryl sulphate. This sample prep tool has virtually zero dead volume, which minimizes the wastage of media. Programmable dispensing volumes range from 200 mL to 4 L in steps of 1-mL for maximum flexibility. Onboard memory stores information of the prior 10 batches of degassed media, and test reports containing data on dissolved oxygen in individual vessels can be printed via the integrated thermal printer. Programmable rinse and cleaning cycle allows the instrument to run through a pre-validated self-cleaning procedure.